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ATCC
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Chem Impex International
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New England Biolabs
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BASF
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Image Search Results
Journal:
Article Title: In Vivo Pharmacodynamic Activity of Daptomycin
doi: 10.1128/AAC.48.1.63-68.2004
Figure Lengend Snippet: In vivo PAE of daptomycin against S. pneumoniae ATCC 10813 after administration of single doses of 2.5 (triangles) and 10 (squares) mg/kg. T > MIC, time that the concentration remains above the MIC.
Article Snippet: The low values for E. faecium may reflect the poor growth of the two strains of E. faecium in control mice (0.34 and 0.37 log 10 CFU/thigh over 24 h). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 4. caption a7 Dose-response curves for daptomycin against various strains of S. pneumoniae . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 5. caption a7 Dose-response curves for daptomycin against various strains of S. aureus (circles) and E. faecium (squares). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism MIC (mg/liter) Static dose (mg/kg/24 h) a 24-h AUC/MIC ratio Peak/MIC ratio Static dose 1 log killing 2 log killing Static dose 1 log killing 2 log killing S. pneumoniae
Techniques: In Vivo, Concentration Assay
Journal:
Article Title: In Vivo Pharmacodynamic Activity of Daptomycin
doi: 10.1128/AAC.48.1.63-68.2004
Figure Lengend Snippet: In vivo PAEs of free and total daptomycin concentrations of against S. aureus and S. pneumoniae
Article Snippet: The low values for E. faecium may reflect the poor growth of the two strains of E. faecium in control mice (0.34 and 0.37 log 10 CFU/thigh over 24 h). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 4. caption a7 Dose-response curves for daptomycin against various strains of S. pneumoniae . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 5. caption a7 Dose-response curves for daptomycin against various strains of S. aureus (circles) and E. faecium (squares). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism MIC (mg/liter) Static dose (mg/kg/24 h) a 24-h AUC/MIC ratio Peak/MIC ratio Static dose 1 log killing 2 log killing Static dose 1 log killing 2 log killing S. pneumoniae
Techniques: In Vivo
Journal:
Article Title: In Vivo Pharmacodynamic Activity of Daptomycin
doi: 10.1128/AAC.48.1.63-68.2004
Figure Lengend Snippet: Static doses of daptomycin for different dosing intervals
Article Snippet: The low values for E. faecium may reflect the poor growth of the two strains of E. faecium in control mice (0.34 and 0.37 log 10 CFU/thigh over 24 h). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 4. caption a7 Dose-response curves for daptomycin against various strains of S. pneumoniae . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 5. caption a7 Dose-response curves for daptomycin against various strains of S. aureus (circles) and E. faecium (squares). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism MIC (mg/liter) Static dose (mg/kg/24 h) a 24-h AUC/MIC ratio Peak/MIC ratio Static dose 1 log killing 2 log killing Static dose 1 log killing 2 log killing S. pneumoniae
Techniques:
Journal:
Article Title: In Vivo Pharmacodynamic Activity of Daptomycin
doi: 10.1128/AAC.48.1.63-68.2004
Figure Lengend Snippet: Dose-response curves for daptomycin against various strains of S. pneumoniae.
Article Snippet: The low values for E. faecium may reflect the poor growth of the two strains of E. faecium in control mice (0.34 and 0.37 log 10 CFU/thigh over 24 h). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 4. caption a7 Dose-response curves for daptomycin against various strains of S. pneumoniae . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 5. caption a7 Dose-response curves for daptomycin against various strains of S. aureus (circles) and E. faecium (squares). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism MIC (mg/liter) Static dose (mg/kg/24 h) a 24-h AUC/MIC ratio Peak/MIC ratio Static dose 1 log killing 2 log killing Static dose 1 log killing 2 log killing S. pneumoniae
Techniques:
Journal:
Article Title: In Vivo Pharmacodynamic Activity of Daptomycin
doi: 10.1128/AAC.48.1.63-68.2004
Figure Lengend Snippet: MICs, static doses, and magnitudes of 24-h AUC/MIC and peak/MIC ratios required to produce a bacteriostatic effect and killing of 1 and 2 log 10 CFU per thigh over 24 h
Article Snippet: The low values for E. faecium may reflect the poor growth of the two strains of E. faecium in control mice (0.34 and 0.37 log 10 CFU/thigh over 24 h). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 4. caption a7 Dose-response curves for daptomycin against various strains of S. pneumoniae . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 5. caption a7 Dose-response curves for daptomycin against various strains of S. aureus (circles) and E. faecium (squares). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism MIC (mg/liter) Static dose (mg/kg/24 h) a 24-h AUC/MIC ratio Peak/MIC ratio Static dose 1 log killing 2 log killing Static dose 1 log killing 2 log killing S. pneumoniae
Techniques:
Journal:
Article Title: In Vivo Pharmacodynamic Activity of Daptomycin
doi: 10.1128/AAC.48.1.63-68.2004
Figure Lengend Snippet: AUC over 24 h for free daptomycin associated with the static dose and doses producing killing of 1 and 2 log10 CFU/thigh for multiple strains of S. pneumoniae and S. aureus.
Article Snippet: The low values for E. faecium may reflect the poor growth of the two strains of E. faecium in control mice (0.34 and 0.37 log 10 CFU/thigh over 24 h). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 4. caption a7 Dose-response curves for daptomycin against various strains of S. pneumoniae . fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 5. caption a7 Dose-response curves for daptomycin against various strains of S. aureus (circles) and E. faecium (squares). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism MIC (mg/liter) Static dose (mg/kg/24 h) a 24-h AUC/MIC ratio Peak/MIC ratio Static dose 1 log killing 2 log killing Static dose 1 log killing 2 log killing S. pneumoniae
Techniques: